Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 525
interventional 461
Observational 61
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug|placebo 155
Drug 119
Dietary Supplement 34
Dietary Supplement|placebo 32
Other 27
Device 24
Procedure 21
Behavioral 9
Other|placebo 6
Diagnostic Test 4
Behavioral|Drug 3
Device|Drug 3
Drug|Other 3
Drug|Procedure 3
Biological|Other 2
Device|Other 2
Device|placebo 2
Dietary Supplement|Drug 2
Other|Procedure 2
Behavioral|Dietary Supplement 1
Behavioral|Other 1
Biological|placebo 1
Combination Product|placebo 1
Device|Diagnostic Test 1
Diagnostic Test|Other 1
Dietary Supplement|Other 1
Drug|Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 172
NA 49
China 21
United Kingdom 20
France 14
Brazil 13
Japan 12
Canada 9
Italy 9
Korea, Republic of 9
United States|Canada 8
Germany 7
Taiwan 7
Denmark 6
Netherlands 6
Sweden 6
Poland 5
Spain 5
Belgium 4
Hong Kong 4
Malaysia 4
Switzerland 4
Ireland 3
Romania 3
Turkey 3
Australia 2
Egypt 2
Finland 2
Indonesia 2
Mexico 2
Norway 2
Pakistan 2
United States|Australia|Germany|Slovakia 2
United States|Belgium|Bulgaria|Canada|Estonia|Germany|Hungary|Israel|Italy|Netherlands|Poland|Serbia|Spain|Ukraine|United Kingdom 2
Australia|Austria|Belgium|Czech Republic|Denmark|Finland|France|Germany|Israel|Netherlands|Poland|Romania|Switzerland|United Kingdom 1
Belgium|Bulgaria|Czech Republic|Denmark|France|Germany|Netherlands|Poland|Romania|United Kingdom 1
Belgium|Czech Republic|Hungary|Italy|Poland|Romania|Slovakia|Spain|Sweden 1
Belgium|Czechia|Finland|Germany|Hungary|Spain 1
Belgium|United States|Canada|France|Netherlands|Poland|United Kingdom 1
Canada|United States 1
Chile 1
China|Australia|Korea, Republic of|Taiwan|Thailand 1
Croatia 1
Czech Republic|France|Germany|Italy|Poland|Sweden|United Kingdom 1
Denmark|Israel|Norway|Spain|United Kingdom 1
Germany|United Kingdom 1
Hong Kong|United States|Australia|Austria|Canada|Denmark|Finland|Hungary|Ireland|Netherlands|New Zealand|Poland|Spain|Sweden|Switzerland|Taiwan|United Kingdom 1
Iran, Islamic Republic of 1
Israel 1
Korea, Republic of|Taiwan 1
Philippines 1
Russian Federation 1
Serbia|Bulgaria|Czechia|Germany|Poland|Portugal|Slovakia|Spain|United Kingdom 1
Slovakia 1
South Africa 1
Spain|United Kingdom 1
Thailand 1
United States|Argentina|Australia|Canada|Czechia|Finland|France|Germany|Hong Kong|Hungary|India|Italy|Korea, Republic of|Netherlands|New Zealand|Pakistan|Peru|Philippines|Poland|Portugal|Russian Federation|South Africa|Spain|Taiwan|Thailand|United Kingdom 1
United States|Australia|Austria|Canada|Czechia|Denmark|France|Germany|Hungary|Israel|Italy|Poland|South Africa|Spain|Sweden|United Kingdom 1
United States|Australia|Belgium|Brazil|Canada|France|Germany|Italy|Mexico|Spain|Sweden|United Kingdom 1
United States|Australia|Belgium|Canada|France|Germany|Italy|Mexico|Portugal|United Kingdom 1
United States|Australia|Canada|China|New Zealand 1
United States|Australia|Canada|Colombia|Korea, Republic of|Spain 1
United States|Australia|Canada|France|Hungary|Netherlands|New Zealand|Norway|South Africa|Spain|Sweden|Switzerland 1
United States|Austria|Canada|Denmark|Estonia|Finland|Germany|Ireland|Poland|United Kingdom 1
United States|Austria|Czechia|Germany|Poland|Spain|United Kingdom 1
United States|Austria|Denmark|Germany|Netherlands|Spain|Sweden|United Kingdom 1
United States|Belgium|Canada|Czech Republic|Hungary|Poland|Slovakia|South Africa|Sweden|United Kingdom 1
United States|Belgium|Canada|France|Netherlands|Poland|United Kingdom 1
United States|Belgium|Croatia|Czech Republic|Hungary|Spain|Sweden|United Kingdom 1
United States|Belgium|United Kingdom 1
United States|Canada|Colombia|Mexico|Peru 1
United States|Czech Republic|Italy|Poland 1
United States|Israel 1

Sites per Study

Site_count Study_Count
1 297
2 21
3 17
4 10
5 2
6 2
7 2
8 2
9 3
10 2
11 6
12 1
13 3
14 4
15 2
16 1
17 1
18 1
19 1
20 1
21 1
24 1
25 1
27 3
33 1
36 2
38 1
39 1
41 1
42 1
43 1
44 1
45 1
46 1
47 1
49 2
50 2
51 1
52 1
53 1
60 3
61 1
62 2
65 1
67 2
69 1
71 1
73 2
77 1
78 1
79 3
82 1
85 2
93 1
95 1
99 1
104 1
105 1
107 1
108 1
111 1
116 2
117 3
118 2
120 1
121 2
140 1
141 1
146 1
150 1
151 1
155 1
162 1
167 1
170 1
186 1
187 1
189 1
191 1
194 1
200 1
220 1
227 1
345 1

Phase

Phase Study_Count
N/A 145
Phase 3 104
Phase 2 95
Phase 4 65
Phase 1 25
Phase 2/Phase 3 13
Phase 1/Phase 2 12
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 67
2 218
3 79
4 29
5 16
6 2
7 1
8 1
9 1
10 1
14 1
25 1
NA 44

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 20.0 4.0000 7 10.0 10.0000 30.0000 30.0000 10.0000
1st Qu. 34.5 39.0000 22 34.5 56.2500 70.0000 181.0000 47.5000
Median 49.0 70.0000 37 49.5 100.0000 76.0000 460.0000 96.0000
Mean 49.0 134.3931 48 56.7 162.4783 238.6923 547.7723 148.9683
3rd Qu. 63.5 120.0000 48 71.5 228.5000 356.0000 700.0000 169.0000
Max. 78.0 4000.0000 214 120.0 1075.0000 951.0000 2370.0000 1400.0000

Trial Group Type

group_type Group_Count
Experimental 520
Placebo Comparator 226
Active Comparator 218
NA 44
Other 27
No Intervention 19
Sham Comparator 11

Intervention Model

intervention_model Study_Count
Parallel Assignment 327
Single Group Assignment 81
Crossover Assignment 37
NA 8
Factorial Assignment 5
Sequential Assignment 3

Primary Purpose

primary_purpose Study_Count
Treatment 360
Prevention 23
Basic Science 17
Diagnostic 15
Other 13
Supportive Care 13
NA 12
Health Services Research 5
Screening 2
Educational/Counseling/Training 1

Observational Studies

Studies by Country

Country Study_Count
United States 22
NA 6
United Kingdom 4
Denmark 3
Italy 3
Belgium 2
Canada 2
China 2
Netherlands 2
Taiwan 2
China|Korea, Republic of|Malaysia|Philippines|Singapore 1
Denmark|Finland|France|Germany|Greece|Italy|Netherlands|Spain|Sweden|United Kingdom 1
Finland 1
Finland|Germany|United Kingdom 1
France 1
Germany|Netherlands|United Kingdom 1
Japan 1
Korea, Republic of 1
Norway 1
Spain 1
Sweden 1
Turkey 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 44
2 5
3 3
8 1
10 1
11 1
13 1
14 1
16 2
30 1
47 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 68.000
Median 137.000
Mean 3113.213
3rd Qu 370.000
Max 120000.000

Observation Model

observational_model Study_Count
Cohort 30
Case-Only 11
Case-Control 7
Case Control 5
Other 4
Case-Crossover 2
Defined Population 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 38
Cross-Sectional 12
Retrospective 7
NA 3
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
China 1
NA 1
Turkey 1

Sites per Study

Site_count Study_Count
1 3

Enrollment Metrics

Measure Registries
Min 94.0000
1st Qu 97.0000
Median 100.0000
Mean 131.3333
3rd Qu 150.0000
Max 200.0000

Registry Model

observational_model Study_Count
Cohort 2
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 3

Follow-up

target_duration Study_Count
1 Day 1
12 Months 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02592200 Effect of Lactobacillus Gasseri DSM 27123 on Functional Constipation in Healthy Women https://ClinicalTrials.gov/show/NCT02592200 Completed BioGaia AB 2016-07-31
NCT04462211 Constipation Bundle/Protocol and the Effect of Adherence in the Incidence of Constipation in Critically Ill Patients https://ClinicalTrials.gov/show/NCT04462211 Recruiting University of Chile 2020-07-31
NCT04458675 Efficacy and Safety of Vibrant Capsule vs. Vibrant Placebo for the Treatment of Chronic Idiopathic Constipation (CIC) https://ClinicalTrials.gov/show/NCT04458675 Completed Vibrant Ltd. 2019-01-07
NCT03879239 Efficacy and Safety of Vibrant Capsule vs. Placebo for the Treatment of Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT03879239 Recruiting Vibrant Ltd. 2021-07-30
NCT03381703 Investigation of the Absorption, Metabolism, and Excretion and the Absolute Bioavailability of YH12852 https://ClinicalTrials.gov/show/NCT03381703 Completed Seoul National University Hospital 2017-03-29
NCT03379038 Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy https://ClinicalTrials.gov/show/NCT03379038 Completed Isra University 2019-01-20
NCT03377322 Trial of Probiotics for Constipation in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT03377322 Completed University of Malaya 2019-01-31
NCT03821532 Adherence/Outcomes After Use of Constipation Action Plan https://ClinicalTrials.gov/show/NCT03821532 Completed Nemours Children’s Clinic 2018-02-01
NCT03819062 Sacral Neuromodulation as Treatment for Chronic Constipation https://ClinicalTrials.gov/show/NCT03819062 Recruiting McMaster University 2021-02-28
NCT03355807 Use of MgSO4 for Pain After Bariatric Surgery https://ClinicalTrials.gov/show/NCT03355807 Completed Yeditepe University Hospital 2017-12-15
NCT03329027 A Pilot Study to Assess the Efficacy and Safety of Various Vibrating Capsule Modes https://ClinicalTrials.gov/show/NCT03329027 Completed Vibrant Ltd. 2018-03-30
NCT03317938 Studies in Patients With Defecatory Disorders https://ClinicalTrials.gov/show/NCT03317938 Recruiting Giome 2020-12-31
NCT03316859 Naloxegol and Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT03316859 Recruiting TriHealth Inc. 2020-12-01
NCT03308461 Fecal Microbiota Transplantation for Constipation https://ClinicalTrials.gov/show/NCT03308461 Completed The Second Hospital of Nanjing Medical University 2017-05-01
NCT03303417 Effect of Kiwifruit on Gastrointestinal Fluid Distribution and Transit in Healthy Volunteers https://ClinicalTrials.gov/show/NCT03303417 Completed University of Nottingham 2017-11-01
NCT03263065 A Study of the Effect of Bran, Psyllium and Nopal on Intestinal Water Content Using Magnetic Resonance Imaging https://ClinicalTrials.gov/show/NCT03263065 Completed University of Nottingham 2018-10-01
NCT03243955 Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation https://ClinicalTrials.gov/show/NCT03243955 Recruiting University of California, Los Angeles 2021-07-01
NCT03234452 Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects. https://ClinicalTrials.gov/show/NCT03234452 Completed Montefarmaco OTC SpA 2016-07-21
NCT03202771 Randomized Controlled Trial of Home Versus Office Biofeedback for Constipation https://ClinicalTrials.gov/show/NCT03202771 Completed Augusta University 2010-12-31
NCT03150212 Effect of Saccharomyces Cerevisiae on the Improvement of Gastro-intestinal Disorders Associated to IBS With C Phenotype https://ClinicalTrials.gov/show/NCT03150212 Completed Lesaffre International 2019-05-09
NCT03120520 An Efficacy and Safety Study of Plecanatide in Adolescents 12 to <18 Years of Age With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT03120520 Completed Bausch Health Americas, Inc. 2018-09-07
NCT03119584 Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation https://ClinicalTrials.gov/show/NCT03119584 Active, not recruiting Texas Tech University Health Sciences Center, El Paso 2020-10-30
NCT03117322 Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation https://ClinicalTrials.gov/show/NCT03117322 Completed Hospital Civil Juan I. Menchaca 2018-12-21
NCT03106857 Effect of Weight Reduction on Constipation https://ClinicalTrials.gov/show/NCT03106857 Completed Ahlia University 2016-09-30
NCT03100851 Effect of Probiotic on Constipation https://ClinicalTrials.gov/show/NCT03100851 Completed China Agricultural University 2016-09-26
NCT03097861 Evaluation of the Bioequivalence of Sprinkle and Capsule Formulations of Lubiprostone, as Compared to Placebo https://ClinicalTrials.gov/show/NCT03097861 Completed Mallinckrodt 2017-08-17
NCT03078634 The Multi-disciplinary Treatment of Functional Gut Disorders Study https://ClinicalTrials.gov/show/NCT03078634 Active, not recruiting St Vincent’s Hospital Melbourne 2019-02-28
NCT03060512 To Evaluate Patient Preference of Movantik and Polyethylene Glycol 3350 for Opioid Induced Constipation https://ClinicalTrials.gov/show/NCT03060512 Completed AstraZeneca 2017-08-23
NCT03060330 Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome https://ClinicalTrials.gov/show/NCT03060330 Recruiting Renmin Hospital of Wuhan University 2022-04-30
NCT03054805 The Effect of Probiotics on Constipation, and Intestinal Microflora in Children With Functional Constipation https://ClinicalTrials.gov/show/NCT03054805 Completed Chang Gung Memorial Hospital 2014-12-31
NCT03054506 The Effect of CSP01 on Chronic Idiopathic Constipation and Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT03054506 Completed Massachusetts General Hospital 2018-05-10
NCT03051399 Clinical Evaluation of the Effects of EpiCor on Digestive Comfort https://ClinicalTrials.gov/show/NCT03051399 Completed ProDigest 2016-01-31
NCT03047629 Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson’s Disease Related Constipation https://ClinicalTrials.gov/show/NCT03047629 Completed Enterin Inc. 2018-04-25
NCT03031977 Visceral Mobilization and Functional Constipation in Stroke Survivors https://ClinicalTrials.gov/show/NCT03031977 Completed University of Sorocaba 2016-10-31
NCT02977286 Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids https://ClinicalTrials.gov/show/NCT02977286 Recruiting Tufts Medical Center 2019-12-31
NCT02961582 Effectiveness and Cost-effectiveness of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation https://ClinicalTrials.gov/show/NCT02961582 Active, not recruiting Maastricht University Medical Center 2021-03-31
NCT02961556 General Clinical Study of AJG555 in Pediatric Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT02961556 Completed Eisai Inc. 2017-06-09
NCT02956187 Treatment of Constipation in Functional Dyspepsia https://ClinicalTrials.gov/show/NCT02956187 Completed Hospital Universitari Vall d’Hebron Research Institute 2017-12-10
NCT02941471 Transabdominal Electrical Stimulation for Constipation https://ClinicalTrials.gov/show/NCT02941471 Completed St Mark’s Hospital Foundation 2015-09-30
NCT03226145 Reclassifying Constipation Using Imaging and Manometry https://ClinicalTrials.gov/show/NCT03226145 Recruiting University of Nottingham 2020-09-30
NCT02877394 Use of a Squatting Assist Device in Patients With Constipation https://ClinicalTrials.gov/show/NCT02877394 Recruiting Mayo Clinic 2023-06-30
NCT02867917 Comparison of Taste and Palatability in Fiber Supplements https://ClinicalTrials.gov/show/NCT02867917 Completed VU University Medical Center 2016-12-31
NCT02863848 Effect of Inulin-type Fructans on Constipated Children. https://ClinicalTrials.gov/show/NCT02863848 Completed Institut Investigacio Sanitaria Pere Virgili 2013-09-30
NCT02844426 Effect of a Synbiotic on Symptoms of Patients With STC https://ClinicalTrials.gov/show/NCT02844426 Completed Jinling Hospital, China 2016-06-30
NCT02838797 RQ-00000010 for Gastroparesis and Constipation in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02838797 Completed Virginia Commonwealth University 2019-08-20
NCT02822508 A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02822508 Completed Braintree Laboratories 2017-04-30
NCT02820714 A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02820714 Completed Braintree Laboratories 2017-01-31
NCT02819310 An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT02819310 Completed Braintree Laboratories 2017-08-31
NCT02819297 BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT02819297 Completed Braintree Laboratories 2017-06-30
NCT02812836 3D High Resolution Manometry and Balloon Expulsion Test in Diagnosis of Dyssynergic Defecation in Children https://ClinicalTrials.gov/show/NCT02812836 Recruiting Medical University of Warsaw 2019-03-01
NCT02812823 Comparison of Anorectal Manometry and 3D Manometry in Diagnosis of Functional Disorders in Children https://ClinicalTrials.gov/show/NCT02812823 Recruiting Medical University of Warsaw 2019-03-31
NCT02809105 A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT02809105 Completed Astellas Pharma Inc 2016-11-14
NCT02795390 Clinical Trial on Palliative Cancer Patients With Constipation https://ClinicalTrials.gov/show/NCT02795390 Completed Hong Kong Baptist University 2018-08-31
NCT02766777 Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation https://ClinicalTrials.gov/show/NCT02766777 Completed Mallinckrodt 2016-11-04
NCT02751411 Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months https://ClinicalTrials.gov/show/NCT02751411 Completed Aboca Spa Societa’ Agricola 2019-12-31
NCT02737059 Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects https://ClinicalTrials.gov/show/NCT02737059 Completed Mayo Clinic 2017-05-10
NCT02729909 Lubiprostone for Chronic Idiopathic Constipation Treatment https://ClinicalTrials.gov/show/NCT02729909 Completed Takeda 2017-04-28
NCT02727751 A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C https://ClinicalTrials.gov/show/NCT02727751 Completed Ardelyx 2017-10-31
NCT02726295 The Efficacy of Mutaflor(E. Coli Nissle 1917, Mutaflor®) for Chronic Constipation:Multicenter Study https://ClinicalTrials.gov/show/NCT02726295 Completed Keimyung University Dongsan Medical Center 2017-10-31
NCT02695719 Lubiprostone for Treatment of Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02695719 Completed Takeda 2017-01-20
NCT02686138 A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C https://ClinicalTrials.gov/show/NCT02686138 Completed Ardelyx 2017-08-31
NCT02665728 A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects https://ClinicalTrials.gov/show/NCT02665728 Completed Braintree Laboratories 2016-04-30
NCT02658201 Ultrafast MRI Imaging to Exclude Constipation https://ClinicalTrials.gov/show/NCT02658201 Completed Sheffield Children’s NHS Foundation Trust 2014-04-30
NCT02651155 Lubiprostone for the Treatment of Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02651155 Completed Takeda 2017-01-11
NCT02649062 Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals https://ClinicalTrials.gov/show/NCT02649062 Completed NGM Biopharmaceuticals, Inc 2017-01-31
NCT02621892 A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C https://ClinicalTrials.gov/show/NCT02621892 Completed Ardelyx 2017-03-31
NCT02590432 An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02590432 Completed Forest Laboratories 2018-02-05
NCT02573922 Opioid Induced Bowel Dysfunction in Patients Undergoing Spinal Surgery https://ClinicalTrials.gov/show/NCT02573922 Completed Kuopio University Hospital 2014-12-31
NCT02566746 Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Medical Treatment https://ClinicalTrials.gov/show/NCT02566746 Active, not recruiting Nantes University Hospital 2022-12-31
NCT04155307 Is the Evaluation of Anal Distensibility by Endoflip® Technique Useful for the Diagnosis of Anismus? https://ClinicalTrials.gov/show/NCT04155307 Recruiting University Hospital, Rouen 2021-12-31
NCT02559570 A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC) https://ClinicalTrials.gov/show/NCT02559570 Completed Forest Laboratories 2018-04-20
NCT02559245 Effect of Flixweed and Fig on Irritable Bowel Syndrome With Predominant Constipation: a Single Blind Randomized Clinical Trial. https://ClinicalTrials.gov/show/NCT02559245 Completed Isfahan University of Medical Sciences 2016-01-31
NCT02559206 Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT02559206 Completed Ironwood Pharmaceuticals, Inc. 2016-09-30
NCT03391635 Efficacy of Electroacupuncture Compared With Transcutaneous Electric Nerve Stimulation for Functional Constipation https://ClinicalTrials.gov/show/NCT03391635 Recruiting Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2019-12-31
NCT02548247 Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation https://ClinicalTrials.gov/show/NCT02548247 Completed Beneo GmbH 2012-05-31
NCT02538367 Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation https://ClinicalTrials.gov/show/NCT02538367 Completed Yuhan Corporation 2016-09-30
NCT02530216 Evaluating the Impact of Automated Evaluation of Gastrointestinal Symptoms (AEGIS) on Clinical Outcomes https://ClinicalTrials.gov/show/NCT02530216 Completed Cedars-Sinai Medical Center 2018-02-07
NCT00006157 Treatment of Functional Bowel Disorders https://ClinicalTrials.gov/show/NCT00006157 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT02493452 Second Plecanatide Study In Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT02493452 Completed Bausch Health Americas, Inc. 2016-11-30
NCT02493036 A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C https://ClinicalTrials.gov/show/NCT02493036 Completed Synthetic Biologics Inc. 2015-12-31
NCT02481947 A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT02481947 Completed Braintree Laboratories 2015-11-30
NCT02467972 Functional Ingredients: Effect in Gastrointestinal System https://ClinicalTrials.gov/show/NCT02467972 Completed University of Sao Paulo 2012-08-31
NCT02461485 Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms https://ClinicalTrials.gov/show/NCT02461485 Completed Danone Research 2016-07-31
NCT02459717 Pre-biotics and Probiotics for Constipation in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02459717 Completed IRCCS Policlinico S. Matteo 2015-10-31
NCT02446080 Drink Milk Consumption Benefits With Culture Probiotic in the Treatment of Constipation https://ClinicalTrials.gov/show/NCT02446080 Completed Centro Universitário Univates 2015-02-28
NCT02436057 Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform https://ClinicalTrials.gov/show/NCT02436057 Completed Cedars-Sinai Medical Center 2015-12-31
NCT02425722 A Study to Evaluate Dose Responses of Efficacy and Safety of ASP0456 in Patient With Chronic Constipation https://ClinicalTrials.gov/show/NCT02425722 Completed Astellas Pharma Inc 2015-10-31
NCT02422329 Changes in Patient Reported Constipation Among Advanced Cancer Patients After Receiving an Educational Intervention https://ClinicalTrials.gov/show/NCT02422329 Completed M.D. Anderson Cancer Center 2018-03-07
NCT02419924 Proof of Concept: “Bottom’s Up” Seat to Treat Constipation https://ClinicalTrials.gov/show/NCT02419924 Completed Mayo Clinic 2016-12-31
NCT02418507 An Evaluation of the Effectiveness of a Proprietary Probiotic Blend on Functional Constipation https://ClinicalTrials.gov/show/NCT02418507 Completed KGK Science Inc. 2016-04-01
NCT02411175 The Efficacy of Individualised Homeopathic Treatment on Constipation https://ClinicalTrials.gov/show/NCT02411175 Completed University of Johannesburg 2015-08-31
NCT02406859 Utility of an Animated Bowel Biofeedback Training Routine to Improve Bowel Function in Individuals With SCI https://ClinicalTrials.gov/show/NCT02406859 Completed VA Office of Research and Development 2017-06-30
NCT02387359 The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C) https://ClinicalTrials.gov/show/NCT02387359 Completed Bausch Health Americas, Inc. 2016-12-31
NCT02373488 The Effects of Connective Tissue Manipulation and Abdominal Massage in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT02373488 Completed Hacettepe University 2018-09-30
NCT02359396 A Randomized, Open-label, Three-arm Study of MZRW on Tolerability, Exposure and Pharmacokinetics https://ClinicalTrials.gov/show/NCT02359396 Completed Hong Kong Baptist University 2015-07-31
NCT02344485 Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02344485 Recruiting New York Institute of Technology 2020-12-31
NCT02343978 Phase II Study of KWA-0711 in Patients With Chronic Constipation (CC) https://ClinicalTrials.gov/show/NCT02343978 Completed Kissei Pharmaceutical Co., Ltd. 2015-05-01
NCT02321124 Connective Tissue Manipulation Improves Symptoms and Quality of Life in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT02321124 Completed Hacettepe University 2015-07-31
NCT02316899 Phase III Study to Evaluate the Efficacy and Safety of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT02316899 Completed Astellas Pharma Inc 2015-09-19
NCT02314936 Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation https://ClinicalTrials.gov/show/NCT02314936 Completed KGK Science Inc. 2016-04-30
NCT02291679 Trial of Linaclotide in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT02291679 Completed Ironwood Pharmaceuticals, Inc. 2015-08-31
NCT02281630 Phase II Dose-Finding Study of KWA-0711 in Patients With Chronic Constipation (CC) https://ClinicalTrials.gov/show/NCT02281630 Completed Kissei Pharmaceutical Co., Ltd. 2015-04-28
NCT02270983 Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain https://ClinicalTrials.gov/show/NCT02270983 Completed Forest Laboratories 2015-08-31
NCT02236533 Healthy Effects of an Innovative Probiotic Pasta https://ClinicalTrials.gov/show/NCT02236533 Completed University of Parma 2014-09-30
NCT02234518 Fibers and Gut Health https://ClinicalTrials.gov/show/NCT02234518 Completed Nestlé 2015-10-31
NCT02220348 A Lactation Study in Women Who Are Breastfeeding or Pumping and Are Receiving Linaclotide Therapeutically https://ClinicalTrials.gov/show/NCT02220348 Completed Forest Laboratories 2019-05-31
NCT02215785 The Effect of Consumption of Kiwifruit on Constipation in Adults https://ClinicalTrials.gov/show/NCT02215785 Completed Jordi Gol i Gurina Foundation 2013-08-31
NCT02211976 Efficacy and Tolerability of Bisacodyl Sugar Coated Tablets, Simeticone Chewing Tablets and Their Combination in Constipation and Bloatedness https://ClinicalTrials.gov/show/NCT02211976 Completed Boehringer Ingelheim 2003-11-30
NCT02194972 Clinical Effects of Soluble Dietary Fiber Supplementation https://ClinicalTrials.gov/show/NCT02194972 Completed Nanjing PLA General Hospital 2012-10-31
NCT02193997 Constipation Fiber Trial https://ClinicalTrials.gov/show/NCT02193997 Completed University of Iowa 2014-07-31
NCT02189707 Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation. https://ClinicalTrials.gov/show/NCT02189707 Completed Danisco Sweeteners Oy 2015-04-30
NCT02187640 Effects of Self-administered Acupressure in Psychiatric Patients With Constipation https://ClinicalTrials.gov/show/NCT02187640 Completed The Hong Kong Polytechnic University 2015-06-30
NCT02183766 GOS Prebiotic Effect in Children Constipation https://ClinicalTrials.gov/show/NCT02183766 Completed University of Campinas, Brazil 2012-03-31
NCT02147574 Anti-peristaltic Ileo-sigmoid Anastomosis for the Treatment of Slow-transit Constipation:Therapeutic Evaluation https://ClinicalTrials.gov/show/NCT02147574 Completed First Affiliated Hospital of Harbin Medical University 2014-01-31
NCT02146053 Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron. https://ClinicalTrials.gov/show/NCT02146053 Completed Medical Research Council 2004-12-31
NCT02144376 MRI and Microbiota Analysis in Constipation https://ClinicalTrials.gov/show/NCT02144376 Completed University of Nottingham 2015-02-28
NCT02140749 Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults https://ClinicalTrials.gov/show/NCT02140749 Completed NIZO Food Research 2014-12-31
NCT02138851 The Effects of a Ficus Carica in Subjects With Functional Constipation https://ClinicalTrials.gov/show/NCT02138851 Completed Chonbuk National University Hospital 2013-06-30
NCT02138136 Lubiprostone for Children With Constipation https://ClinicalTrials.gov/show/NCT02138136 Completed Mallinckrodt 2017-05-01
NCT02137642 Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT02137642 Completed Motus Therapeutics, Inc. 2014-11-30
NCT02137213 Feasibility Study of Oral Naloxone for Treatment of Methadone-induced Constipation https://ClinicalTrials.gov/show/NCT02137213 Completed Centre for Addiction and Mental Health 2015-03-31
NCT02136693 Psyllium Fiber Versus Placebo in Early Treatment After STARR for Obstructed Defecation: a Double-blind RCT https://ClinicalTrials.gov/show/NCT02136693 Completed University of Milano Bicocca 2011-12-31
NCT02122471 12-Week Study of Plecanatide for CIC (The National CIC3 Study) https://ClinicalTrials.gov/show/NCT02122471 Completed Bausch Health Americas, Inc. 2015-05-31
NCT02116101 Intestinal Health and Blood Lipid Adjustment https://ClinicalTrials.gov/show/NCT02116101 Completed Bright Dairy & Food Co., Ltd 2013-04-30
NCT02110719 Decreasing Narcotics in Advanced Pelvic Surgery https://ClinicalTrials.gov/show/NCT02110719 Completed Hartford Hospital 2015-07-31
NCT02103556 Edible Oils in the Treatment of Constipation of Hemodialysis Patients https://ClinicalTrials.gov/show/NCT02103556 Completed Federal University of São Paulo 2013-04-30
NCT02099591 Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients https://ClinicalTrials.gov/show/NCT02099591 Active, not recruiting Kyowa Kirin Pharmaceutical Development Ltd 2021-07-31
NCT02091115 Consumption of Milk Drink and Constipation https://ClinicalTrials.gov/show/NCT02091115 Completed Centro Universitário Univates 2013-07-31
NCT02082457 Efficacy and Safety of YKP10811 in Subjects With Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT02082457 Completed SK Chemicals Co., Ltd. 2014-12-31
NCT02078323 Investigation of Linaclotide’s Effect on the Bi-directional Brain and Gut Axis in IBS-C Patients https://ClinicalTrials.gov/show/NCT02078323 Completed Augusta University 2017-10-04
NCT02073006 A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation https://ClinicalTrials.gov/show/NCT02073006 Completed Atlantia Food Clinical Trials 2014-07-31
NCT01309841 Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01309841 Completed AstraZeneca 2012-08-31
NCT01306448 Safety Evaluation of the Vibrating Capsule https://ClinicalTrials.gov/show/NCT01306448 Completed Vibrant Ltd. 2014-04-30
NCT01301781 BLI801 Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT01301781 Completed Braintree Laboratories 2011-05-31
NCT01288508 Investigation of Supra Fiber in the Treatment of Adults With Constipation https://ClinicalTrials.gov/show/NCT01288508 Completed Augusta University 2014-06-30
NCT01275755 Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain https://ClinicalTrials.gov/show/NCT01275755 Completed Cubist Pharmaceuticals LLC 2011-07-15
NCT02047045 Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT02047045 Completed Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2016-08-31
NCT02042183 Efficacy and Safety of Lubiprostone in Pediatric Subjects Aged ≥ 6 Years to < 18 Years With Functional Constipation https://ClinicalTrials.gov/show/NCT02042183 Completed Mallinckrodt 2016-07-31
NCT02030756 Performance, Efficacy and Safety of Vibrating Capsule in Aiding Constipated Individuals https://ClinicalTrials.gov/show/NCT02030756 Completed Vibrant Ltd. 2016-01-31
NCT02012543 Effect of Agar Administration on Defecation and Fecal Condition in Chronic Constipated Patients https://ClinicalTrials.gov/show/NCT02012543 Completed Showa Inan General Hospital 2014-10-31
NCT02004288 The Role of Lactobacillus Reuteri in Children and Adolescents With Anorexia Nervosa https://ClinicalTrials.gov/show/NCT02004288 Completed BioGaia AB 2016-09-30
NCT01993940 Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01993940 Completed Shionogi Inc. 2015-06-09
NCT01993875 Pharmacodynamic, Pharmacokinetic, and Tolerability Study of a Liquid Form of Lubiprostone in Adult Subjects With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01993875 Completed Mallinckrodt 2014-01-31
NCT01989234 A Multicenter, Double-Blind, Randomized, Placebo-Controlled, 12-Week, Dose-Range-Finding Trial of YKP10811 Capsules Administered Once Daily to Subjects With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01989234 Completed SK Life Science, Inc. 2014-09-30
NCT01985867 Lcr35 for Children With Functional Constipation https://ClinicalTrials.gov/show/NCT01985867 Completed Medical University of Warsaw 2016-11-30
NCT01983306 Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT01983306 Completed Bausch Health Americas, Inc. 2014-09-30
NCT01982240 12-Week Study of Plecanatide for CIC (The CIC3 Study) https://ClinicalTrials.gov/show/NCT01982240 Completed Bausch Health Americas, Inc. 2015-04-30
NCT01965652 Long Term Safety of Naldemedine https://ClinicalTrials.gov/show/NCT01965652 Completed Shionogi Inc. 2016-01-12
NCT01965158 Efficacy and Safety of Naldemedine in the Treatment of Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01965158 Completed Shionogi Inc. 2015-01-22
NCT04451096 Probiotics-prebiotic Fiber Therapy in Parkinson’s Disease Patients With Constipation https://ClinicalTrials.gov/show/NCT04451096 Completed National University of Malaysia 2019-02-28
NCT01946334 Does Body Position Influence Pressure Recording by High-resolution Manometry ? https://ClinicalTrials.gov/show/NCT01946334 Completed Assistance Publique Hopitaux De Marseille 2014-03-31
NCT01938196 A Single-blind, Dose-titration Study of KWA-0711 in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT01938196 Completed Kissei Pharmaceutical Co., Ltd. 2014-01-31
NCT01933100 Comparison of Rice Based-meal on Functional Constipation in Young Korean Women https://ClinicalTrials.gov/show/NCT01933100 Completed Chonbuk National University Hospital 2012-08-31
NCT01931930 Effect of Perilla Extract on Improvement on Gastrointestinal Discomfort https://ClinicalTrials.gov/show/NCT01931930 Completed Amino Up Chemicals Co., Ltd. 2012-11-30
NCT01923428 The Efficacy of AZD1722 in Constipation Predominant Irritable Bowel Syndrome (IBS-C) https://ClinicalTrials.gov/show/NCT01923428 Completed Ardelyx 2014-10-31
NCT01919697 Open-label Extension (OLE) Study of Plecanatide for Chronic Idiopathic Constipation (CIC) https://ClinicalTrials.gov/show/NCT01919697 Completed Bausch Health Americas, Inc. 2016-01-31
NCT01917773 Effect of Octreotide on the Colonic Motility in Pediatric Patients https://ClinicalTrials.gov/show/NCT01917773 Completed Indiana University 2014-06-30
NCT01895543 Safety and Tolerability Extension Trial for Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01895543 Completed Ferring Pharmaceuticals 2015-05-31
NCT01880424 A Phase 3, International, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Efficacy and Safety Trial of Linaclotide Administered Orally for 12 Weeks to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT01880424 Completed AstraZeneca 2015-05-31
NCT01879605 Study About Effect of Preoperative Bowel Preparation Versus no Bowel Preparation Before Spinal Surgery https://ClinicalTrials.gov/show/NCT01879605 Completed Oslo University Hospital 2009-12-31
NCT01874301 Probiotics and Gut Health https://ClinicalTrials.gov/show/NCT01874301 Completed Nestlé 2015-10-31
NCT01870700 Lactobacillus Reuteri in Adult With Functional Chronic Constipation https://ClinicalTrials.gov/show/NCT01870700 Completed Catholic University, Italy 2012-06-30
NCT01867944 Perineal Self-Acupressure https://ClinicalTrials.gov/show/NCT01867944 Completed University of California, Los Angeles 2014-06-30
NCT01862341 The Effect of Milk Powder With Fiber and Probiotics on Digestive Habits and General Health Well-being of Selected Filipino Mothers. https://ClinicalTrials.gov/show/NCT01862341 Completed Fonterra Research Centre 2013-07-31
NCT01859065 “Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits” https://ClinicalTrials.gov/show/NCT01859065 Completed Bronx-Lebanon Hospital Center Health Care System 2012-04-30
NCT01847950 Effects of scFOS on Stool Frequency in People With Functionnal Constipation https://ClinicalTrials.gov/show/NCT01847950 Completed Syral 2013-12-31
NCT01837940 Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population https://ClinicalTrials.gov/show/NCT01837940 Completed Örebro University, Sweden 2013-09-30
NCT01834729 Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions https://ClinicalTrials.gov/show/NCT01834729 Completed Mayo Clinic 2017-09-06
NCT01825434 Effect of Yogurt With Polydextrose,L Acidophilus and B Lactis in Chronic Constipation https://ClinicalTrials.gov/show/NCT01825434 Completed University of Campinas, Brazil 2010-06-30
NCT01810653 A Study to Compare the Effect of Transipeg 2.95 g or Forlax Junior 4 g in Children With Constipation https://ClinicalTrials.gov/show/NCT01810653 Completed Bayer 2008-12-31
NCT01809587 IQP-PO-101 for the Regulation of Bowel Movement Frequency https://ClinicalTrials.gov/show/NCT01809587 Completed InQpharm Group 2013-08-31
NCT01802112 Randomised Controlled Trial of Efficacy of Resistant Maltodextrins on Reducing Colonic Transit Time https://ClinicalTrials.gov/show/NCT01802112 Completed San Antonio Technologies - San Antonio Catholic University of Murcia 2013-03-31
NCT01773096 Methylnaltrexone Use for Opioid-induced Postoperative Constipation https://ClinicalTrials.gov/show/NCT01773096 Completed Shriners Hospitals for Children 2015-05-31
NCT01726751 Spinal Cord Stimulation for Pain Relief in Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT01726751 Completed Uppsala University 2014-04-30
NCT01726504 The Efficacy and Safety Study of Electro-acupuncture for Severe Chronic Functional Constipation https://ClinicalTrials.gov/show/NCT01726504 Completed Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2014-10-31
NCT01722318 The Plecanatide Irritable Bowel Syndrome With Constipation Study (IBS-C) https://ClinicalTrials.gov/show/NCT01722318 Completed Bausch Health Americas, Inc. 2014-04-30
NCT01714843 A Study to Evaluate the Effect of ASP0456 in Patients With Constipation Predominant Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT01714843 Completed Astellas Pharma Inc 2013-12-07
NCT01710579 Normal Values in Ano-rectal 3D High Resolution Manometry https://ClinicalTrials.gov/show/NCT01710579 Completed Hospices Civils de Lyon 2014-09-30
NCT01707667 Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity https://ClinicalTrials.gov/show/NCT01707667 Completed Shire 2013-11-30
NCT01695850 A Double-blinded,Double-dummy Clinical Trial of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation https://ClinicalTrials.gov/show/NCT01695850 Completed Hong Kong Baptist University 2015-08-31
NCT01691742 MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery https://ClinicalTrials.gov/show/NCT01691742 Completed Duke University 2015-03-31
NCT01687985 A Safety and Efficacy Evaluation of BLI801 Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT01687985 Completed Braintree Laboratories 2013-03-31
NCT01684319 Milk-induced Gastrointestinal Symptoms in Infants https://ClinicalTrials.gov/show/NCT01684319 Completed University Hospital, Geneva 2013-08-31
NCT01680432 Effect of the Consumption of a Cheese Enriched With Probiotic Organisms in Improving Symptoms of Constipation https://ClinicalTrials.gov/show/NCT01680432 Completed Centro Universitário Univates 2012-05-31
NCT01677715 Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System https://ClinicalTrials.gov/show/NCT01677715 Completed Inner Mongolia Yili Industrial Group Co., Ltd 2011-11-30
NCT01674530 Evaluation of Clinical Equivalence Between Two Lubiprostone Products in the Treatment of Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01674530 Completed Dr. Reddy’s Laboratories Limited 2014-01-31
NCT01674192 Prucalopride Subjects With Renal Impairment https://ClinicalTrials.gov/show/NCT01674192 Completed Movetis 1999-08-31
NCT01674166 Single Dose Pharmacokinetics of Prucalopride in Paediatric Subjects, With Functional Faecal Retention https://ClinicalTrials.gov/show/NCT01674166 Completed Movetis 1999-05-31
NCT01655771 TD-1211 Single-Dose Study in Elderly and Young Healthy Subjects https://ClinicalTrials.gov/show/NCT01655771 Completed Theravance Biopharma 2013-02-28
NCT01642914 Safety and Efficacy of Linaclotide in Patients With Chronic Constipation and Prominent Abdominal Bloating https://ClinicalTrials.gov/show/NCT01642914 Completed Forest Laboratories 2013-05-31
NCT01629303 Efficacy of Sacral Nerve Modulation in Severe Refractory Constipation https://ClinicalTrials.gov/show/NCT01629303 Completed University Hospital, Bordeaux 2013-11-30
NCT01623609 Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol https://ClinicalTrials.gov/show/NCT01623609 Completed AstraZeneca 2012-09-30
NCT01622972 Mode of Action of Moviprep https://ClinicalTrials.gov/show/NCT01622972 Completed University of Nottingham 2014-02-28
NCT01609608 Whole-Body Vibration for Functional Constipation https://ClinicalTrials.gov/show/NCT01609608 Completed Changhua Christian Hospital 2010-10-31
NCT01607060 Impact of Laxative Therapy With Lactulose in the Evolution of Organ Dysfunction in Critically Ill Patients. https://ClinicalTrials.gov/show/NCT01607060 Completed Federal University of São Paulo 2012-04-30
NCT01603719 Efficacy and Safety of an Infant Formula With Milkfat and Prebiotics https://ClinicalTrials.gov/show/NCT01603719 Completed Waldkrankenhaus Protestant Hospital, Spandau 2014-10-31
NCT01600001 A Exploratory Study of KWA-0711 in Patients With Chronic Idiopathic Constipation (CIC) https://ClinicalTrials.gov/show/NCT01600001 Completed Kissei Pharmaceutical Co., Ltd. NA
NCT01594619 Study in Healthy Volunteers to Investigate the Effects of Diltiazem on the Pharmacokinetics of Naloxegol https://ClinicalTrials.gov/show/NCT01594619 Completed AstraZeneca 2012-08-31
NCT01592734 Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children https://ClinicalTrials.gov/show/NCT01592734 Completed Azienda Policlinico Umberto I 2011-11-30
NCT01566409 Maintenance Treatment for Children With Constipation https://ClinicalTrials.gov/show/NCT01566409 Completed Vejle Hospital 2015-04-30
NCT01533870 Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118 https://ClinicalTrials.gov/show/NCT01533870 Completed AstraZeneca 2012-05-31
NCT01533155 Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118 https://ClinicalTrials.gov/show/NCT01533155 Completed AstraZeneca 2012-09-30
NCT01523184 A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation https://ClinicalTrials.gov/show/NCT01523184 Completed SK Life Science, Inc. 2013-11-30
NCT01515501 Endoscopic Mucosal Resection for the Diagnosis of a-Ganglionosis, a Controlled Prospective Trial (EDGE Trial) https://ClinicalTrials.gov/show/NCT01515501 Completed Massachusetts General Hospital 2012-02-29
NCT01513811 Itopride as an Adjuvant for Bowel Preparation in Patients With Chronic Constipation is Effective https://ClinicalTrials.gov/show/NCT01513811 Completed Shanghai Jiao Tong University School of Medicine 2011-11-30
NCT01474499 A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation https://ClinicalTrials.gov/show/NCT01474499 Completed Ferring Pharmaceuticals 2012-03-31
NCT01469819 Lubiprostone Effect on Gastrointestinal Tract Transit Times Measured by Smartpill in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT01469819 Completed Texas Tech University Health Sciences Center, El Paso 2015-02-28
NCT01463293 B. Lactis HN019 for Functional Constipation https://ClinicalTrials.gov/show/NCT01463293 Completed Fonterra Research Centre 2013-03-31
NCT01460225 Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01460225 Completed Dartmouth-Hitchcock Medical Center 2010-12-31
NCT01459926 A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT01459926 Completed Theravance Biopharma 2012-05-31
NCT01447849 Lubiprostone and Mucus Secretion in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT01447849 Completed Texas Tech University Health Sciences Center, El Paso 2012-11-30
NCT01443403 A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy https://ClinicalTrials.gov/show/NCT01443403 Completed Shionogi Inc. 2012-08-22
NCT01438567 A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy https://ClinicalTrials.gov/show/NCT01438567 Completed Mundipharma Research GmbH & Co KG 2014-02-28
NCT01429987 The Plecanatide Chronic Idiopathic Constipation (CIC) Study https://ClinicalTrials.gov/show/NCT01429987 Completed Bausch Health Americas, Inc. 2012-12-31
NCT01427283 A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain https://ClinicalTrials.gov/show/NCT01427283 Completed Purdue Pharma LP 2014-10-31
NCT01427270 Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) for Uncontrolled Moderate - Severe Low Back Pain https://ClinicalTrials.gov/show/NCT01427270 Completed Purdue Pharma LP 2014-10-31
NCT01424228 Evaluation of Long-term Prucalopride Treatment With Chronic Constipation in Subjects Aged ≥ 18 Years https://ClinicalTrials.gov/show/NCT01424228 Completed Shire 2012-12-31
NCT01418092 ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT01418092 Completed Alkermes, Inc. 2012-06-30
NCT01416909 Managing Medication-induced Constipation in Cancer: A Clinical Trial https://ClinicalTrials.gov/show/NCT01416909 Completed H. Lee Moffitt Cancer Center and Research Institute 2013-08-31
NCT01411501 Efficacy and Safety of Acupuncture for Functional Constipation https://ClinicalTrials.gov/show/NCT01411501 Completed Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2014-10-31
NCT01401985 A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT01401985 Completed Theravance Biopharma 2012-05-31
NCT01395524 A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01395524 Completed AstraZeneca 2012-09-30
NCT01382797 ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT01382797 Completed Alkermes, Inc. 2012-04-30
NCT01375712 Efficacy Evaluation of Probiotic Product on Bowel Habits in Healthy Subjects https://ClinicalTrials.gov/show/NCT01375712 Completed Yakult Honsha Co., LTD 2011-10-31
NCT01372423 Evaluation of Clinical Equivalence Between Two Lubiprostone Products https://ClinicalTrials.gov/show/NCT01372423 Completed Anchen Pharmaceuticals, Inc 2012-06-30
NCT01368562 Compassionate Use Study of Methylnaltrexone https://ClinicalTrials.gov/show/NCT01368562 Completed Bausch Health Americas, Inc. 2008-06-02
NCT03348007 Clinical Trial Assessing the Efficacy and Safety of Hépar® in Chronic Constipation https://ClinicalTrials.gov/show/NCT03348007 Completed Quanta Medical 2016-07-22
NCT01354080 The Effectiveness of Massage in Treating Constipation https://ClinicalTrials.gov/show/NCT01354080 Completed University School of Physical Education in Wroclaw 2010-02-28
NCT01348152 Effect of TU-100 in Patients With Functional Constipation https://ClinicalTrials.gov/show/NCT01348152 Completed Tsumura USA 2013-07-31
NCT01340053 A Study to Evaluate the Safety and Efficacy of RDX5791 for the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS-C) https://ClinicalTrials.gov/show/NCT01340053 Completed Ardelyx 2011-12-31
NCT01336205 Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01336205 Completed AstraZeneca 2012-12-31
NCT01335386 Investigation of KLYX in Patients With Constipation https://ClinicalTrials.gov/show/NCT01335386 Completed Ferring Pharmaceuticals 2010-07-31
NCT01333787 Dietary Fiber Mixture in Constipated Pediatric Patients https://ClinicalTrials.gov/show/NCT01333787 Completed Federal University of São Paulo 2009-01-31
NCT01333540 A Study to Assess the Safety, Tolerability and Clinical Activity of TD−1211 in Patients With Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT01333540 Completed Theravance Biopharma 2012-05-31
NCT01331213 Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT01331213 Completed Mayo Clinic 2013-02-28
NCT01323790 Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation https://ClinicalTrials.gov/show/NCT01323790 Completed AstraZeneca 2012-09-30
NCT04437147 Effect of Probiotics on Functional Constipation in Healthy Adults https://ClinicalTrials.gov/show/NCT04437147 Recruiting University of Sorocaba 2020-06-30
NCT04382456 Evaluation of Acacia Gum on Microbiome and Bowel Function in Participants With Chronic Constipation https://ClinicalTrials.gov/show/NCT04382456 Recruiting Alpinia Laudanum Institute of Phytopharmaceutical Sciences AG 2020-09-30
NCT04380090 Post-Operative Constipation Following Total Knee Arthroplasty https://ClinicalTrials.gov/show/NCT04380090 Recruiting The Cleveland Clinic 2020-12-31
NCT04373772 Effect of Abdominal Massage on Bowel Evacuation After Cranial Surgery https://ClinicalTrials.gov/show/NCT04373772 Completed Mersin University 2016-02-28
NCT04318808 Effect of Laser Acupuncture on Constipation in Patients With Advanced Cancer https://ClinicalTrials.gov/show/NCT04318808 Recruiting Chang Gung Memorial Hospital 2022-02-28
NCT04304170 Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit https://ClinicalTrials.gov/show/NCT04304170 Completed CEN Biotech 2018-03-15
NCT04293159 Effect of Probiotic on Constipation in Patients With Parkinson’s Disease https://ClinicalTrials.gov/show/NCT04293159 Recruiting University of Salerno 2020-12-31
NCT04283266 Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults https://ClinicalTrials.gov/show/NCT04283266 Completed Vesale Pharmaceutica 2018-10-29
NCT04282551 The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation https://ClinicalTrials.gov/show/NCT04282551 Recruiting Wageningen University and Research 2021-11-30
NCT03461848 CYPHP Evelina London Evaluation https://ClinicalTrials.gov/show/NCT03461848 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2020-12-31
NCT04263896 Bowel Function After Minimally Invasive Hysterectomy https://ClinicalTrials.gov/show/NCT04263896 Recruiting University of Chicago 2020-06-30
NCT04262752 MOWOOT Device to Treat Constipation in Adults https://ClinicalTrials.gov/show/NCT04262752 Completed usMIMA S.L. 2019-05-13
NCT04197869 Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy https://ClinicalTrials.gov/show/NCT04197869 Recruiting Northwell Health 2021-12-09
NCT04182633 MTT for Children With ASD Who Have Gastrointestinal Disorders https://ClinicalTrials.gov/show/NCT04182633 Recruiting Arizona State University 2021-06-30
NCT04166058 Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C https://ClinicalTrials.gov/show/NCT04166058 Enrolling by invitation Allergan 2023-02-28
NCT04132804 Effect of Tai Chi as Treatment for IBS-C https://ClinicalTrials.gov/show/NCT04132804 Recruiting Massachusetts General Hospital 2021-08-01
NCT04086134 Physiological, Microbiological and Metabolomic Effects of Fruit Products https://ClinicalTrials.gov/show/NCT04086134 Recruiting King’s College London 2021-03-31
NCT04083521 Effect of Bacillus Subtilis DE111® on Daily Bowel Movements https://ClinicalTrials.gov/show/NCT04083521 Completed Deerland Enzymes 2017-08-31
NCT04082689 Bowel And Bladder Function in Infant Toilet Training https://ClinicalTrials.gov/show/NCT04082689 Recruiting Dalarna County Council, Sweden 2022-03-31
NCT04071444 Exploring the Effects of a Baduanjin Program on the Symptoms of Constipation in Patients With Schizophrenia Spectrum https://ClinicalTrials.gov/show/NCT04071444 Completed National Yang Ming University 2019-07-01
NCT04035616 Probiotics in Elderly Patients With Medical Conditions https://ClinicalTrials.gov/show/NCT04035616 Completed Universiti Kebangsaan Malaysia Medical Centre 2018-12-31
NCT04032262 Parkinson’s Disease and Digestive Health https://ClinicalTrials.gov/show/NCT04032262 Recruiting Augusta University 2020-07-31
NCT04028258 Effect of a Mixture of Fibers and Carbohydrates on Intestinal Transit in Children Diagnosed With Functional Constipation https://ClinicalTrials.gov/show/NCT04028258 Recruiting Laboratorios Ordesa 2020-12-31
NCT04014413 Safety and Efficacy of Fecal Microbiota Transplantation https://ClinicalTrials.gov/show/NCT04014413 Recruiting Chinese University of Hong Kong 2023-10-31
NCT03981510 Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation https://ClinicalTrials.gov/show/NCT03981510 Recruiting University of Aarhus 2023-12-31
NCT03885973 Lactobacillus Plantarum IS 10560 Supplementation in Women With Functional Constipation https://ClinicalTrials.gov/show/NCT03885973 Completed Fakultas Kedokteran Universitas Indonesia 2018-08-22
NCT03845673 Fiber Regimens for Constipation Symptoms https://ClinicalTrials.gov/show/NCT03845673 Completed University of Texas Southwestern Medical Center 2005-07-31
NCT03842007 Understanding Mechanisms of Normal and Disordered Defecation https://ClinicalTrials.gov/show/NCT03842007 Recruiting Mayo Clinic 2022-12-31
NCT03829358 The Role of Probiotics in Improving Quality of Life in Women With Functional Constipation https://ClinicalTrials.gov/show/NCT03829358 Completed Fakultas Kedokteran Universitas Indonesia 2018-07-21
NCT03797586 Effect of Electroacupuncture on Opioid-induced Constipation in Patients With Cancer https://ClinicalTrials.gov/show/NCT03797586 Recruiting Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2021-03-31
NCT03781791 Orally Administered ENT-01 for Parkinson’s Disease-Related Constipation (KARMET) https://ClinicalTrials.gov/show/NCT03781791 Active, not recruiting Enterin Inc. 2020-08-31
NCT03763175 Efficacy and Safety of SYN-010 in IBS-C https://ClinicalTrials.gov/show/NCT03763175 Recruiting Cedars-Sinai Medical Center 2020-10-30
NCT03751267 Effects of Paediatric Tuina (Massage) on Constipation and Related Symptoms Among the Pre-school Aged Children https://ClinicalTrials.gov/show/NCT03751267 Recruiting The University of Hong Kong 2019-09-17
NCT03707002 Effect of scFOS on Increase in Stool Frequency in Constipated People https://ClinicalTrials.gov/show/NCT03707002 Completed Syral 2017-01-31
NCT03687814 Low FODMAP Plus PEG 3350 for the Treatment of Patients With Irritable Bowel Syndrome-Constipation https://ClinicalTrials.gov/show/NCT03687814 Recruiting University of Michigan 2020-11-03
NCT03687268 Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation https://ClinicalTrials.gov/show/NCT03687268 Recruiting Develco Pharma Schweiz AG 2019-11-30
NCT02270450 S1316, Surgery or Non-Surgical Management in Treating Patients With Intra-Abdominal Cancer and Bowel Obstruction https://ClinicalTrials.gov/show/NCT02270450 Recruiting Southwest Oncology Group 2020-10-31
NCT03614000 Early Screening of Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation. https://ClinicalTrials.gov/show/NCT03614000 Recruiting Universitair Ziekenhuis Brussel 2021-08-12
NCT03596905 Efficacy and Safety of Plecanatide in Children 6 to <18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT03596905 Recruiting Bausch Health Americas, Inc. 2020-12-31
NCT03591393 Pelvic Floor Dysfunction and Its Influence on Body Image and Sexual Function https://ClinicalTrials.gov/show/NCT03591393 Recruiting Universitaire Ziekenhuizen Leuven 2021-06-30
NCT02228616 Efficacy and Safety of Prucalopride in Combination With Polyethylene Glycol or Lactulose in Women With Chronic Constipation https://ClinicalTrials.gov/show/NCT02228616 Completed Xian-Janssen Pharmaceutical Ltd. 2016-09-28
NCT03569527 Kiwifruit, Prunes, & Fiber for Abdominal and Bowel Symptoms in US Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT03569527 Completed University of Michigan 2019-10-10
NCT03564249 Magnetic Resonance Imaging in Paediatric Constipation https://ClinicalTrials.gov/show/NCT03564249 Completed Nottingham University Hospitals NHS Trust 2019-06-30
NCT03523715 Prunes for Gastrointestinal Function After Gynecologic Surgery https://ClinicalTrials.gov/show/NCT03523715 Recruiting University of Southern California 2019-06-30
NCT03499808 S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis https://ClinicalTrials.gov/show/NCT03499808 Active, not recruiting Southwest Oncology Group 2021-10-30
NCT03462199 A Study to Evaluate the Efficacy of the Investigational Products on Complete Spontaneous Bowel Movements in Participants Who Normally Have ≤ 3 Complete Spontaneous Bowel Movements Per Week But Are Otherwise Healthy https://ClinicalTrials.gov/show/NCT03462199 Recruiting AIDP, Inc. 2019-11-30
NCT01267370 Soy Polysaccharide Fiber for the Treatment of Chronic Constipation in Children: a Randomized, Double-blind Trial https://ClinicalTrials.gov/show/NCT01267370 Completed Federal University of São Paulo 2002-12-31
NCT01251822 Comparator Study of PEG 3350 Versus Prucalopride in Females With Chronic Constipation https://ClinicalTrials.gov/show/NCT01251822 Completed Norgine 2011-09-30
NCT01244945 Lactobacillus Reuteri DSM 17938 in Functional Constipation https://ClinicalTrials.gov/show/NCT01244945 Completed Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 2013-12-31
NCT01243723 Study Assessing the Efficacy of Eductyl® for the Treatment of Patients With Dyschesia https://ClinicalTrials.gov/show/NCT01243723 Completed Laboratoires Techni Pharma 2012-03-31
NCT01236534 Lubiprostone in Patients With Multiple Sclerosis Associated Constipation https://ClinicalTrials.gov/show/NCT01236534 Completed University of Rochester 2012-01-31
NCT01230840 Effect of Wheat Dextrin on Calcium and Magnesium Absorption https://ClinicalTrials.gov/show/NCT01230840 Completed Creighton University 2010-06-30
NCT01207427 Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain https://ClinicalTrials.gov/show/NCT01207427 Completed Cubist Pharmaceuticals LLC 2011-04-18
NCT01212445 Dose-Finding Trial of Polyethylene Glycol 3350 Laxative Plus Electrolytes for the Treatment of Constipation (Protocol P07515) https://ClinicalTrials.gov/show/NCT01212445 Completed Bayer 2011-11-30
NCT01190020 Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation. https://ClinicalTrials.gov/show/NCT01190020 Completed Augusta University 2012-03-31
NCT01186770 A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain https://ClinicalTrials.gov/show/NCT01186770 Completed Bausch Health Americas, Inc. 2011-09-08
NCT01185431 The Effects of a Ficus Carica on Improvement in Bowl Movements in Female Volunteer With Functional Constipation https://ClinicalTrials.gov/show/NCT01185431 Completed Chonbuk National University Hospital 2011-02-28
NCT01180725 Investigation of Dried Plums in the Treatment of Adults With Constipation https://ClinicalTrials.gov/show/NCT01180725 Completed University of Iowa NA
NCT01170039 The Effectiveness of Lubiprostone in Constipated Diabetics https://ClinicalTrials.gov/show/NCT01170039 Completed Emory University 2014-10-31
NCT01162863 Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation https://ClinicalTrials.gov/show/NCT01162863 Completed University of Michigan 2012-12-31
NCT01161784 The Effects of a Probiotic Fermented Milk on Functional Constipation in Adults https://ClinicalTrials.gov/show/NCT01161784 Completed International Medical University 2010-06-30
NCT01151878 Glucomannan for Childhood Functional Constipation. https://ClinicalTrials.gov/show/NCT01151878 Completed Medical University of Warsaw 2010-06-30
NCT01149200 Proof-of-Principle Study of TC-6499 in the Treatment of Constipation Predominant Irritable Bowel Syndrome (IBS) https://ClinicalTrials.gov/show/NCT01149200 Completed Targacept Inc. 2010-10-31
NCT01147926 Evaluation of Prucalopride in Male Subjects With Chronic Constipation. https://ClinicalTrials.gov/show/NCT01147926 Completed Shire 2013-10-31
NCT01139216 Effect of TU-100 on Rectal Compliance, Rectal Sensation and Small Bowel and Colonic Transit in Females With Constipation https://ClinicalTrials.gov/show/NCT01139216 Completed Tsumura USA 2012-11-30
NCT01116206 An Efficacy and Safety Study of Prucalopride in Participants With Chronic Constipation https://ClinicalTrials.gov/show/NCT01116206 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2011-03-31
NCT01109511 A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy https://ClinicalTrials.gov/show/NCT01109511 Completed Oslo University Hospital 2011-06-30
NCT01102036 Effects of Cultura Yoghurt in Relation to Transit Time and Digestive Discomfort in Healthy Women and Men https://ClinicalTrials.gov/show/NCT01102036 Completed Good Food Practice, Sweden 2010-05-31
NCT01100151 ALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT01100151 Completed Alkermes, Inc. 2010-12-31
NCT01096290 Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications https://ClinicalTrials.gov/show/NCT01096290 Completed University of South Alabama 2012-09-30
NCT01085643 Effect of Lubiprostone on Small Bowel Contractions in Female Patients With Constipation Irritable Bowel Syndrome (C-IBS) https://ClinicalTrials.gov/show/NCT01085643 Completed Cedars-Sinai Medical Center 2010-12-31
NCT01070615 Study to Evaluate Long-Term Tolerability and Safety of Oral Prucalopride in Chronic Constipation https://ClinicalTrials.gov/show/NCT01070615 Completed Movetis 2000-11-30
NCT01056107 Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients https://ClinicalTrials.gov/show/NCT01056107 Completed Mayo Clinic 2011-12-31
NCT01053962 SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01053962 Completed Bausch Health Americas, Inc. 2010-08-31
NCT01040637 A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT01040637 Completed Theravance Biopharma 2010-10-31
NCT01038687 Effect of Ileal Bile Acid Transporter Inhibitor in Functional Constipation https://ClinicalTrials.gov/show/NCT01038687 Completed Mayo Clinic 2011-01-31
NCT01027260 Study to Evaluate the Role of Itopride HCI in Patients With Irritable Bowel Syndrome With Predominant Constipation https://ClinicalTrials.gov/show/NCT01027260 Completed Abbott 2010-08-31
NCT01007123 Study of Elobixibat (A3309) in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT01007123 Completed Albireo 2010-10-31
NCT01004393 Methylnaltrexone for Opioid-induced Constipation in Cancer Patients https://ClinicalTrials.gov/show/NCT01004393 Completed University of Vermont 2013-12-31
NCT00994851 Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment. https://ClinicalTrials.gov/show/NCT00994851 Completed Sanofi 2012-08-31
NCT00992576 Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain https://ClinicalTrials.gov/show/NCT00992576 Completed Mundipharma Research GmbH & Co KG 2011-11-30
NCT00988286 Mechanism of Action of Biofeedback Therapy https://ClinicalTrials.gov/show/NCT00988286 Completed Augusta University 2015-12-31
NCT00987844 Study to Evaluate Long-Term Safety, Tolerability, and Satisfaction With Prucalopride in Chronic Constipation https://ClinicalTrials.gov/show/NCT00987844 Completed Movetis 2000-11-30
NCT00984334 Naloxone SR Capsules in Patients With Opioid Induced Constipation https://ClinicalTrials.gov/show/NCT00984334 Completed S.L.A. Pharma AG 2012-01-31
NCT00982839 Rectal Sensory Training - A Study of Two Techniques https://ClinicalTrials.gov/show/NCT00982839 Completed Augusta University 2014-07-31
NCT00948818 Trial of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT00948818 Completed Forest Laboratories 2010-07-31
NCT00945334 Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome https://ClinicalTrials.gov/show/NCT00945334 Completed Cedars-Sinai Medical Center 2013-06-30
NCT00938717 Trial of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT00938717 Completed Ironwood Pharmaceuticals, Inc. 2010-09-30
NCT00934479 Intestinal Microecology in Chronic Constipation https://ClinicalTrials.gov/show/NCT00934479 Completed Mayo Clinic 2012-02-29
NCT00931853 Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC). https://ClinicalTrials.gov/show/NCT00931853 Completed Sanofi 2011-12-31
NCT00912301 Cheno Effect on Transit in Health and IBS-C https://ClinicalTrials.gov/show/NCT00912301 Completed Mayo Clinic 2009-11-30
NCT00910832 Efficacy of Eductyl® Versus Placebo for Treatment of Dyschesia https://ClinicalTrials.gov/show/NCT00910832 Completed Laboratoires Techni Pharma 2011-12-31
NCT00908076 Amitiza in Constipation Associated With PD (Parkinson’s Disease) https://ClinicalTrials.gov/show/NCT00908076 Completed Baylor College of Medicine 2010-10-31
NCT00906971 Physiotherapeutic Intervention in Children With Chronic Functional Constipation https://ClinicalTrials.gov/show/NCT00906971 Completed Universidade Federal de Pernambuco 2010-02-28
NCT00903747 Thorough Corrected QT Interval (QTc) Study To Evaluate Possible Effects of Prucalopride on ECG Parameters https://ClinicalTrials.gov/show/NCT00903747 Completed Movetis 2009-04-30
NCT00902837 OXN PR Compared to OxyPR to Demonstrate Non-inferiority in Pain & Locomotor Function & Improvement in Symptoms of Constipation in OA Subjects https://ClinicalTrials.gov/show/NCT00902837 Completed Mundipharma Research GmbH & Co KG 2010-04-30
NCT00902031 Effectiveness of Docusate in Preventing/Treating Constipation in Palliative Care Patients https://ClinicalTrials.gov/show/NCT00902031 Completed University of Alberta 2010-10-31
NCT00872430 Laxative Effectiveness of a Phytotherapeutic Tea https://ClinicalTrials.gov/show/NCT00872430 Completed Hospital de Clinicas de Porto Alegre 2002-12-31
NCT00869830 The Effectiveness of Biofeedback Treatment in Constipated Patients With Idiopathic Parkinson’s Disease https://ClinicalTrials.gov/show/NCT00869830 Completed Asan Medical Center 2008-08-31
NCT00868985 Effects of Oral PEG 3350 on Electrolyte Balance https://ClinicalTrials.gov/show/NCT00868985 Completed Norgine 2008-08-31
NCT00844831 Effects of Lubiprostone on Small Bowel and Colonic Bacteria: A Correlation Study With Segmental and Whole Gut Transit https://ClinicalTrials.gov/show/NCT00844831 Completed University of Louisville 2011-05-31
NCT04159350 Point-of-care Anorectal Testing to Predict Outcomes With Biofeedback Therapy: Clinical Trial https://ClinicalTrials.gov/show/NCT04159350 Recruiting Dartmouth-Hitchcock Medical Center 2022-12-31
NCT04110145 Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation https://ClinicalTrials.gov/show/NCT04110145 Recruiting Allergan 2023-02-28
NCT03764995 The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation https://ClinicalTrials.gov/show/NCT03764995 Recruiting Hacettepe University 2019-10-01
NCT00794924 Probiotics and Hospital Outcome in the Elderly https://ClinicalTrials.gov/show/NCT00794924 Completed Kaplan-Harzfeld Medical Center 2005-01-31
NCT03909204 LAPEC for the Treatment of Severe Constipation https://ClinicalTrials.gov/show/NCT03909204 Recruiting University Hospital Trnava 2021-05-01
NCT03279341 Effect of PEG, Bisacodyl and Prucalopride on Colonic Motility in Healthy Subjects https://ClinicalTrials.gov/show/NCT03279341 Completed University Hospital, Gasthuisberg 2016-03-31
NCT02234219 Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung’s Disease: A Prospective Multicenter Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT02234219 Recruiting Tongji Hospital 2019-07-11
NCT01957046 A Single-arm, Study to Assess the Effect and Tolerability of Standardised Laxative Therapy (SLT) for the Reversal of Opioid-induced Constipation (OIC). https://ClinicalTrials.gov/show/NCT01957046 Completed Mundipharma Research GmbH & Co KG 2014-08-31
NCT01937663 A Single-blind, Dose-tapering Study of KWA-0711 in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT01937663 Completed Kissei Pharmaceutical Co., Ltd. 2014-01-31
NCT01885104 Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003) https://ClinicalTrials.gov/show/NCT01885104 Completed Bayer 2013-09-30
NCT01781104 Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT01781104 Completed Motus Therapeutics, Inc. 2014-09-30
NCT01670669 Prucalopride in Paediatric Subjects, With Functional Faecal Retention https://ClinicalTrials.gov/show/NCT01670669 Completed Movetis 1999-07-31
NCT01582659 Outpatient Treatment of Constipation in Children https://ClinicalTrials.gov/show/NCT01582659 Completed Vejle Hospital 2014-10-31
NCT00804141 Study Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT00804141 Completed Bausch Health Americas, Inc. 2010-09-20
NCT04026113 Linaclotide Safety and Efficacy, Functional Constipation, in Pediatric Participants 6 to 17 Years of Age https://ClinicalTrials.gov/show/NCT04026113 Recruiting Allergan 2022-01-31
NCT03573908 A Trial of Linaclotide 290 μg in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT03573908 Completed Ironwood Pharmaceuticals, Inc. 2019-03-13
NCT03103958 Effects of Probiotic on Modulation of the Intestinal Microbiota in Constipated Patients https://ClinicalTrials.gov/show/NCT03103958 Completed Farmoquimica S.A. 2016-08-09
NCT02732743 Food Supplement Physiomanna® Baby in Pediatric Patients https://ClinicalTrials.gov/show/NCT02732743 Completed Iuppa Industriale Srl 2016-04-30
NCT02495623 A Study of the Effect of SYN-010 on Subjects With IBS-C https://ClinicalTrials.gov/show/NCT02495623 Completed Synthetic Biologics Inc. 2015-10-31
NCT02423564 A Study Investigating the Effect of Digesta-Lac in Healthy Adults With Occasional Constipation https://ClinicalTrials.gov/show/NCT02423564 Completed KGK Science Inc. 2016-04-12
NCT01682798 Study of Yili “Changqing” Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System https://ClinicalTrials.gov/show/NCT01682798 Completed Inner Mongolia Yili Industrial Group Co., Ltd 2009-06-30
NCT01330381 Prucalopride in Pediatric Subjects With Functional Constipation https://ClinicalTrials.gov/show/NCT01330381 Completed Shire 2013-03-31
NCT00788658 Cognitive Behaviour Therapy for Patients With IBS https://ClinicalTrials.gov/show/NCT00788658 Completed Rabin Medical Center 2010-12-31
NCT00784277 A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease https://ClinicalTrials.gov/show/NCT00784277 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2009-07-31
NCT00770432 Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216) https://ClinicalTrials.gov/show/NCT00770432 Completed Bayer 2008-01-31
NCT00765999 An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT00765999 Completed Forest Laboratories 2012-01-31
NCT00765882 Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00765882 Completed Forest Laboratories 2009-07-31
NCT00763399 Effect of Probiotics on Intestinal Bacterial Population and Immune Modulation https://ClinicalTrials.gov/show/NCT00763399 Completed Chang Gung Memorial Hospital 2010-05-31
NCT00746200 Acupuncture for Chronic Constipation https://ClinicalTrials.gov/show/NCT00746200 Completed National Taiwan University Hospital 2010-04-30
NCT00745147 Comparison of TCM and Laxatives for Adults With Chronic Constipation https://ClinicalTrials.gov/show/NCT00745147 Completed National Taiwan University Hospital 2009-10-31
NCT00741936 An Effectiveness and Safety Study of Chinese Herbal Medicine for Functional Constipation https://ClinicalTrials.gov/show/NCT00741936 Completed Hong Kong Baptist University 2009-11-30
NCT00735605 Comparative Study Between Surgical and Non Surgical Treatment of Anismus in Patients https://ClinicalTrials.gov/show/NCT00735605 Completed Mansoura University 2010-01-31
NCT00730171 An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT00730171 Completed Ironwood Pharmaceuticals, Inc. 2012-03-31
NCT00730015 Trial of Linaclotide in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00730015 Completed Ironwood Pharmaceuticals, Inc. 2009-08-31
NCT00712543 A Preference Study Comparing Kristalose® and Liquid Lactulose https://ClinicalTrials.gov/show/NCT00712543 Completed Cumberland Pharmaceuticals 2009-09-30
NCT00706004 Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic Fibrosis https://ClinicalTrials.gov/show/NCT00706004 Completed University of Arkansas 2009-12-31
NCT00672477 Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness https://ClinicalTrials.gov/show/NCT00672477 Completed Bausch Health Americas, Inc. 2013-02-28
NCT00672139 Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness https://ClinicalTrials.gov/show/NCT00672139 Completed Bausch Health Americas, Inc. 2013-01-31
NCT00662363 Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation https://ClinicalTrials.gov/show/NCT00662363 Completed Shirley Ryan AbilityLab 2011-10-31
NCT00640146 Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures https://ClinicalTrials.gov/show/NCT00640146 Completed Bausch Health Americas, Inc. 2009-01-21
NCT00631813 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00631813 Completed Movetis 1997-04-30
NCT00627692 Evaluation of the Safety and Tolerability of Prucalopride in Constipated Elderly Subjects Living in a Nursing Facility https://ClinicalTrials.gov/show/NCT00627692 Completed Movetis 2000-05-31
NCT00603681 Comparison of PEG Solutions With and Without Electrolytes in the Treatment of Constipation https://ClinicalTrials.gov/show/NCT00603681 Completed Orion Corporation, Orion Pharma 2008-07-31
NCT00617513 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00617513 Completed Movetis 1996-03-31
NCT00611299 Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults https://ClinicalTrials.gov/show/NCT00611299 Completed University of Copenhagen NA
NCT00605644 Study Evaluating MOA-728 Oral for the Treatment of OIBD in Subjects With Chronic Non-Malignant Pain https://ClinicalTrials.gov/show/NCT00605644 Completed Bausch Health Americas, Inc. 2008-05-31
NCT00600119 A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC) https://ClinicalTrials.gov/show/NCT00600119 Completed AstraZeneca 2009-03-31
NCT00598338 Efficacy and Safety Study of Prucalopride for the Re-Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00598338 Completed Movetis 2000-02-29
NCT00596596 Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT00596596 Completed Movetis 1997-06-30
NCT00584571 Randomized Controlled Trial of Treating Rectal Hypersensitivity - Comparing Escitalopram With Sensory Adaptation Training https://ClinicalTrials.gov/show/NCT00584571 Active, not recruiting Augusta University 2015-12-31
NCT00583609 A Pilot Study of a New PEG3350 Dose Formulation For Use in Constipated Children https://ClinicalTrials.gov/show/NCT00583609 Completed Braintree Laboratories 2008-07-31
NCT00583154 A Pilot Efficacy Evaluation of BLI-801 as a Laxative in Constipated Adults https://ClinicalTrials.gov/show/NCT00583154 Completed Braintree Laboratories 2008-01-31
NCT00577018 Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00577018 Completed Movetis 1999-09-30
NCT00576810 Sodium Picosulphate vs. Placebo in Functional Constipation https://ClinicalTrials.gov/show/NCT00576810 Completed Boehringer Ingelheim 2009-01-31
NCT00576511 Effect of Prucalopride in Patients With Severe Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT00576511 Completed Movetis 1996-02-29
NCT00575614 Prucalopride in Patients With Chronic Idiopathic Constipation https://ClinicalTrials.gov/show/NCT00575614 Completed Movetis 1999-03-31
NCT00571896 The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery https://ClinicalTrials.gov/show/NCT00571896 Completed Hartford Hospital 2009-06-30
NCT00547586 Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain https://ClinicalTrials.gov/show/NCT00547586 Completed Bausch Health Americas, Inc. 2008-02-29
NCT01212146 Probiotic-enriched Artichoke in Functional Constipation https://ClinicalTrials.gov/show/NCT01212146 Completed Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 2011-01-31
NCT00529087 Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain https://ClinicalTrials.gov/show/NCT00529087 Completed Bausch Health Americas, Inc. 2008-12-31
NCT00526097 Dulcolax vs Placebo in Functional Constipation https://ClinicalTrials.gov/show/NCT00526097 Completed Boehringer Ingelheim 2009-06-30
NCT00522093 Efficacy and Safety of TJ-100 in the Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00522093 Completed Showa Inan General Hospital 2008-03-31
NCT00521872 Stapled Trans Anal Rectal Resection (STARR) for Outlet Obstruction: Functional and Morphological Outcome https://ClinicalTrials.gov/show/NCT00521872 Completed University of Zurich NA
NCT00513656 A Study Comparing Oxycodone to Oxycodone/Naloxone in Moderate to Severe, Chronic Cancer Pain https://ClinicalTrials.gov/show/NCT00513656 Completed Mundipharma Research GmbH & Co KG 2010-03-31
NCT00508482 A Clinical Standardization Study of the Preferred Acupuncture Treatment Protocol to Treat Functional Constipation https://ClinicalTrials.gov/show/NCT00508482 Completed Guang’anmen Hospital of China Academy of Chinese Medical Sciences 2011-09-30
NCT00502957 Biofeedback Treatment for Functional Constipation https://ClinicalTrials.gov/show/NCT00502957 Completed University of California, San Francisco NA
NCT00488215 A Trial in Healthy Volunteers, to Evaluate the Tolerability and Cardiac Safety of Prucalopride https://ClinicalTrials.gov/show/NCT00488215 Completed Movetis 2000-03-31
NCT00488137 Efficacy and Safety Study of Prucalopride to Treat Chronic Constipation https://ClinicalTrials.gov/show/NCT00488137 Completed Movetis 1999-07-31
NCT00487422 Efficacy and Safety Study of Prucalopride for the Treatment of Elderly Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00487422 Completed Movetis 1999-09-30
NCT00485940 Efficacy and Safety Study of Prucalopride for the Treatment of Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00485940 Completed Movetis 1999-05-31
NCT00483886 Efficacy and Safety Study of Prucalopride for the Treatment of Chronic Constipation https://ClinicalTrials.gov/show/NCT00483886 Completed Movetis 1999-05-31
NCT00460811 Randomized, Double-blind, Dose-range-finding, Phase 2 Study of Linaclotide Administered to Patients With Irritable Bowel Syndrome With Constipation (IBS-C) https://ClinicalTrials.gov/show/NCT00460811 Completed Ironwood Pharmaceuticals, Inc. 2008-02-29
NCT00452335 Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation https://ClinicalTrials.gov/show/NCT00452335 Completed Mallinckrodt 2008-10-31
NCT00444158 Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects https://ClinicalTrials.gov/show/NCT00444158 Completed Bausch Health Americas, Inc. NA
NCT00412152 Oxycodone-naloxone in Relieving Opioid-related Constipation https://ClinicalTrials.gov/show/NCT00412152 Completed Mundipharma Research GmbH & Co KG 2008-04-30
NCT00412100 Oxycodone-naloxone Prolonged Release Tablets in Relieving Opioid-related Constipation https://ClinicalTrials.gov/show/NCT00412100 Completed Mundipharma Research GmbH & Co KG 2008-07-31
NCT00404040 Movicol in Childhood Constipation (ProMotion Study) https://ClinicalTrials.gov/show/NCT00404040 Completed Norgine NA
NCT00403897 An Open Single Centre Study To Assess Treatment of Chronic Constipation in Children https://ClinicalTrials.gov/show/NCT00403897 Completed Norgine NA
NCT00403819 Study to Examine the Efficacy and Safety of Movicol in the Treatment of Chronic Constipation in Children https://ClinicalTrials.gov/show/NCT00403819 Completed Norgine NA
NCT00402337 Dose-range-finding, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00402337 Completed Ironwood Pharmaceuticals, Inc. 2007-12-31
NCT00402038 Study of Methylnaltrexone (MNTX) for the Relief of Constipation https://ClinicalTrials.gov/show/NCT00402038 Completed Bausch Health Americas, Inc. 2005-10-31
NCT00401362 A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients https://ClinicalTrials.gov/show/NCT00401362 Completed Bausch Health Americas, Inc. 2005-02-28
NCT00399542 Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT00399542 Completed Mallinckrodt 2006-07-31
NCT00391820 Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial) https://ClinicalTrials.gov/show/NCT00391820 Completed Theravance Biopharma NA
NCT00380250 Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation https://ClinicalTrials.gov/show/NCT00380250 Completed Mallinckrodt NA
NCT00936884 Study Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-Constipation https://ClinicalTrials.gov/show/NCT00936884 Completed Bausch Health Americas, Inc. 2013-11-30
NCT00368823 A Trial of Point of Care Information in Ambulatory Pediatrics https://ClinicalTrials.gov/show/NCT00368823 Completed University of Washington NA
NCT00366431 Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain https://ClinicalTrials.gov/show/NCT00366431 Completed Bausch Health Americas, Inc. NA
NCT00364169 Prevention of Constipation: Systematic Nursing Interventions to Reduce Postoperative Constipation After Thoracic Surgery https://ClinicalTrials.gov/show/NCT00364169 Completed Rigshospitalet, Denmark 2006-12-31
NCT00354575 Effect of Chinese Herb on Chronic Constipation for Residents in Long-Term Care Units https://ClinicalTrials.gov/show/NCT00354575 Completed National Taiwan University Hospital 2008-02-29
NCT00345397 A Colonic Tube to Improve Bowel Function in Spinal Cord Injury https://ClinicalTrials.gov/show/NCT00345397 Completed VA Office of Research and Development 2014-03-31
NCT00319670 A Pilot Study of a New MiraLax® Dose Formulation For Use in Constipated Children https://ClinicalTrials.gov/show/NCT00319670 Completed Braintree Laboratories 2006-05-31
NCT00311350 Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects https://ClinicalTrials.gov/show/NCT00311350 Completed Bausch Health Americas, Inc. NA
NCT00306748 Phase 2 Study of MD-1100 Acetate Administered for 14 Days to Patients Meeting Criteria for Chronic Constipation https://ClinicalTrials.gov/show/NCT00306748 Completed Ironwood Pharmaceuticals, Inc. NA
NCT00299975 A Dose Determination Study of Chinese Herbal Medicine for Functional Constipation https://ClinicalTrials.gov/show/NCT00299975 Completed Hong Kong Baptist University 2007-08-31
NCT00286520 Treatment of Fecal Incontinence and Constipation in Patients With Spinal Cord Injury https://ClinicalTrials.gov/show/NCT00286520 Completed University of Aarhus NA
NCT00276406 Use of Pyridostigmine for Constipation in Diabetics https://ClinicalTrials.gov/show/NCT00276406 Completed Mayo Clinic 2010-10-31
NCT00276354 Study of Long-term Use of Forlax® in Elderly Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00276354 Completed Ipsen NA
NCT00268879 Investigation of the Safety and Efficacy of Renzapride in Constipation Predominant Irritable Bowel Syndrome (IBS) https://ClinicalTrials.gov/show/NCT00268879 Completed Alizyme 2008-01-31
NCT00259922 Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain https://ClinicalTrials.gov/show/NCT00259922 Completed Cubist Pharmaceuticals LLC 2006-06-30
NCT00258193 Phase 2 Study of MD-1100 Acetate on Gastrointestinal Transit in Patients With C-IBS https://ClinicalTrials.gov/show/NCT00258193 Completed Ironwood Pharmaceuticals, Inc. NA
NCT00256984 Study of Stapled Transanal Rectal Resection (STARR) Surgery in Refractory Constipation Associated With Obstructive Defecation Syndrome (ODS) https://ClinicalTrials.gov/show/NCT00256984 Completed Ethicon Endo-Surgery 2008-03-01
NCT00256932 Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain https://ClinicalTrials.gov/show/NCT00256932 Completed Cubist Pharmaceuticals LLC NA
NCT00255372 To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence. https://ClinicalTrials.gov/show/NCT00255372 Completed Ipsen 2008-05-20
NCT00241722 Long-Term Safety Evaluation Of Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain https://ClinicalTrials.gov/show/NCT00241722 Completed Cubist Pharmaceuticals LLC 2007-02-01
NCT00220090 DARWIN Study: A Randomization/Withdrawal Efficacy Study of Dexloxiglumide in Constipation-Predominant Irritable Bowel Syndrome (C-IBS) https://ClinicalTrials.gov/show/NCT00220090 Completed Rottapharm 2006-09-30
NCT00215566 A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of DDP733 for IBS-c https://ClinicalTrials.gov/show/NCT00215566 Completed Dynogen Pharmaceuticals NA
NCT00200005 Sacral Nerve Stimulation for Anal Incontinence and Bowel Control https://ClinicalTrials.gov/show/NCT00200005 Completed MedtronicNeuro 2006-12-31
NCT00171522 Preference of Tegaserod vs. PEG 3350 in Patients With Constipation https://ClinicalTrials.gov/show/NCT00171522 Completed Novartis NA
NCT00164125 An Open Label Study of Chronic Polyethyleneglycol3350 Use in Constipated Patients https://ClinicalTrials.gov/show/NCT00164125 Completed Braintree Laboratories 2004-11-30
NCT00157638 Integrating Family Medicine and Pharmacy to Advance Primary Care Therapeutics https://ClinicalTrials.gov/show/NCT00157638 Completed McMaster University NA
NCT00153153 Extended Use of Polyethyleneglycol3350 Laxative in Constipated Patients https://ClinicalTrials.gov/show/NCT00153153 Completed Braintree Laboratories 2004-12-31
NCT00153140 Polyethyleneglycol3350 vs Tegaserod in Treatment of Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00153140 Completed Braintree Laboratories 2004-10-31
NCT00153127 Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications https://ClinicalTrials.gov/show/NCT00153127 Completed Braintree Laboratories 2004-09-30
NCT00153114 PolyethyleneGlycol3350 Laxative vs Placebo in Constipated Children https://ClinicalTrials.gov/show/NCT00153114 Completed Braintree Laboratories 2004-09-30
NCT00149877 Efficacy, Safety and Tolerability of Tegaserod in Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00149877 Completed Novartis NA
NCT00141089 Assessment of Efficacy and Safety of Tegaserod in Male Patients With Chronic Constipation. https://ClinicalTrials.gov/show/NCT00141089 Completed Novartis NA
NCT00139568 An Evaluation of the Efficacy and Safety of Tegaserod 6 mg Bid Given Orally to Chinese Patients With Chronic Constipation https://ClinicalTrials.gov/show/NCT00139568 Completed Novartis NA
NCT00127257 Biofeedback for Dyssynergic Constipation https://ClinicalTrials.gov/show/NCT00127257 Completed National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) NA
NCT00101998 Study Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain Medication https://ClinicalTrials.gov/show/NCT00101998 Completed Cubist Pharmaceuticals LLC 2006-05-01
NCT00004911 Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction https://ClinicalTrials.gov/show/NCT00004911 Completed Northwestern University 2003-02-28
NCT00004910 Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction https://ClinicalTrials.gov/show/NCT00004910 Completed Northwestern University 2003-02-28
NCT00004895 Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery https://ClinicalTrials.gov/show/NCT00004895 Completed Northwestern University 2002-10-31
NCT00796354 Constipation Associated With Irritable Bowel Syndrome (IBS-C) https://ClinicalTrials.gov/show/NCT00796354 Completed Norgine 2010-02-28

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03336034 Assessment of Responsiveness to Treatment by Experience Sampling Method https://ClinicalTrials.gov/show/NCT03336034 Recruiting Maastricht University Medical Center 2021-01-31
NCT03143517 Fecal Calprotectin Collection Protocol https://ClinicalTrials.gov/show/NCT03143517 Completed DiaSorin Inc. 2018-08-23
NCT02977858 ISE to Support Constipation Management https://ClinicalTrials.gov/show/NCT02977858 Completed Children’s Hospital Medical Center, Cincinnati 2018-06-01
NCT02961465 Effectiveness and Safety of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation https://ClinicalTrials.gov/show/NCT02961465 Recruiting Maastricht University Medical Center 2021-12-31
NCT02884167 Multidimensional Risk Factor Assessment in Constipation https://ClinicalTrials.gov/show/NCT02884167 Completed Queen Mary University of London 2017-06-30
NCT02813616 Factors Affecting Dissatisfaction to Treatments in Patients With Chronic Constipation and IBS With Constipation https://ClinicalTrials.gov/show/NCT02813616 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2018-07-31
NCT02813369 Naloxegol Health Outcome Post Authorisation Safety Study https://ClinicalTrials.gov/show/NCT02813369 Recruiting Kyowa Kirin Pharmaceutical Development Ltd 2023-12-31
NCT02813356 Naloxegol US PMR CV Safety. https://ClinicalTrials.gov/show/NCT02813356 Active, not recruiting AstraZeneca 2023-12-31
NCT02813148 Naloxegol Drug Utilization PASS https://ClinicalTrials.gov/show/NCT02813148 Recruiting Kyowa Kirin Pharmaceutical Development Ltd 2020-12-31
NCT02577471 The Function of Gastrointestinal Tract During Pregnancy https://ClinicalTrials.gov/show/NCT02577471 Completed Kuopio University Hospital 2012-10-31
NCT02442115 Impact of Improving GI Symptoms on Autism Symptoms and Oxidative Stress https://ClinicalTrials.gov/show/NCT02442115 Recruiting Children’s Hospital Los Angeles 2019-12-31
NCT02428790 Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury https://ClinicalTrials.gov/show/NCT02428790 Completed University of Aarhus 2015-11-30
NCT02246647 Biomarkers for Intestinal Permeability in Patients With Constipation https://ClinicalTrials.gov/show/NCT02246647 Completed Mayo Clinic 2016-12-08
NCT01300897 Investigation of Cortico-Rectal Pathways in Healthy Subjects and Constipated Patients https://ClinicalTrials.gov/show/NCT01300897 Active, not recruiting Augusta University 2015-12-31
NCT01300884 Sierra High Definition Ano-Rectal Manometry https://ClinicalTrials.gov/show/NCT01300884 Completed Augusta University 2011-12-31
NCT01928953 Longitudinal Study of Patients With Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT01928953 Completed AstraZeneca 2014-12-31
NCT01911559 Effectiveness of Standing Frame on Constipation in Children With Cerebral Palsy https://ClinicalTrials.gov/show/NCT01911559 Completed University of Modena and Reggio Emilia 2015-02-28
NCT01902537 An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation https://ClinicalTrials.gov/show/NCT01902537 Completed Janssen Korea, Ltd., Korea 2013-04-30
NCT01880294 A Study to Assess Different Diagnostic Criteria of Chronic Constipation in Asia https://ClinicalTrials.gov/show/NCT01880294 Completed Johnson & Johnson Pte Ltd 2013-12-31
NCT01812733 Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives https://ClinicalTrials.gov/show/NCT01812733 Completed Mundipharma AB 2015-06-30
NCT01793753 Effect of Propofol on Internal Anal Sphincter Pressure During ARM https://ClinicalTrials.gov/show/NCT01793753 Completed Massachusetts General Hospital 2013-06-30
NCT01695915 Diurnal Variation in Rectal Diameter https://ClinicalTrials.gov/show/NCT01695915 Completed Vejle Hospital 2012-10-31
NCT01618292 Cohort Study of Bowel Function Following Robotic-assisted Laparoscopic Sacrocolpopexy https://ClinicalTrials.gov/show/NCT01618292 Completed Atlantic Health System 2012-08-31
NCT01523288 The Intestinal Function in People With Prader-Willi Syndrome https://ClinicalTrials.gov/show/NCT01523288 Completed Aarhus University Hospital 2012-01-31
NCT01399294 Cross Sectional Study of Constipation in Advanced Cancer Patients https://ClinicalTrials.gov/show/NCT01399294 Completed Yan Chai Hospital 2010-07-31
NCT04404933 Study of Opioid-Induced Constipation 2 Project https://ClinicalTrials.gov/show/NCT04404933 Completed Royal Surrey County Hospital NHS Foundation Trust 2019-08-30
NCT04350112 Study of Opioid-Induced Constipation 1 Project https://ClinicalTrials.gov/show/NCT04350112 Completed Royal Surrey County Hospital NHS Foundation Trust 2019-08-30
NCT04309019 Constipation, Gut Microbiome, and Microbial-derived Uremic Toxins From the Gut Microbiota in HD Patients https://ClinicalTrials.gov/show/NCT04309019 Recruiting Tungs’ Taichung Metroharbour Hospital 2020-12-31
NCT04307121 Association of Constipation Inflammatory and Microbial Translocation Markers https://ClinicalTrials.gov/show/NCT04307121 Recruiting Tungs’ Taichung Metroharbour Hospital 2020-12-31
NCT04306939 Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study https://ClinicalTrials.gov/show/NCT04306939 Recruiting University of Pittsburgh 2025-12-01
NCT04294550 Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol https://ClinicalTrials.gov/show/NCT04294550 Recruiting Fondazione ANT Italia ONLUS 2020-12-31
NCT04253652 Investigating the Effects of Iron on the Gastrointestinal Tract https://ClinicalTrials.gov/show/NCT04253652 Active, not recruiting The Functional Gut Clinic 2021-09-30
NCT04214470 A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS https://ClinicalTrials.gov/show/NCT04214470 Recruiting ProgenaBiome 2023-03-31
NCT04148248 A Pilot Study to Explore the Role of Gut Flora in Chronic Constipation https://ClinicalTrials.gov/show/NCT04148248 Recruiting ProgenaBiome 2023-03-31
NCT04106232 Microbiome Analysis of Constipated Versus Non-constipation Patients https://ClinicalTrials.gov/show/NCT04106232 Recruiting HyGIeaCare, Inc. 2020-07-24
NCT04102527 Evaluation of the Impact of Transit Troubles in Patients Undergoing Peritoneal Dialysis https://ClinicalTrials.gov/show/NCT04102527 Recruiting Centre Hospitalier de Vichy 2023-12-31
NCT04068415 Development of a Constipation Risk Assessment Scale for Hospitalized Patients. https://ClinicalTrials.gov/show/NCT04068415 Completed University Hospital, Bordeaux 2014-04-16
NCT04060121 Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders https://ClinicalTrials.gov/show/NCT04060121 Recruiting Indiana University 2020-08-31
NCT04014816 Gastrointestinal Dysfunction During Enteral Nutrition in Critically Ill Patients https://ClinicalTrials.gov/show/NCT04014816 Completed Ayancık State Hospital 2015-07-01
NCT03937739 Nutrition and Constipation at Inguinal Hernia Patients https://ClinicalTrials.gov/show/NCT03937739 Completed Istanbul University 2019-03-01
NCT03720613 Risk of Major Adverse Cardiovascular Events for Naldemedine and Other Medications for Opioid Induced Constipation in Adults With Chronic Non-Cancer Pain https://ClinicalTrials.gov/show/NCT03720613 Recruiting BioDelivery Sciences International 2025-11-01
NCT03638440 Real World Observational Study of Naloxegol for Patients With Cancer Pain Diagnosed With OIC. https://ClinicalTrials.gov/show/NCT03638440 Recruiting Kyowa Kirin Pharmaceutical Development Ltd 2019-11-30
NCT03551873 A Postmarketing Study of Plecanatide in Breast Milk of Lactating Women Treated With TRULANCE® https://ClinicalTrials.gov/show/NCT03551873 Completed Bausch Health Americas, Inc. 2018-12-14
NCT03487640 Surgical Treatment for ODS With Rectal Prolapse Surgical Treatment for Rectal Prolapse https://ClinicalTrials.gov/show/NCT03487640 Recruiting Third Military Medical University 2020-01-08
NCT03471728 Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases) https://ClinicalTrials.gov/show/NCT03471728 Recruiting Astellas Pharma Inc 2021-12-31
NCT00909116 International Multicenter Prospective Transtar Registry https://ClinicalTrials.gov/show/NCT00909116 Completed Ethicon Endo-Surgery (Europe) GmbH 2012-04-30
NCT00888147 Fiber Formula Study Among Radiation Oncology Patients https://ClinicalTrials.gov/show/NCT00888147 Completed Mayo Clinic 2011-07-31
NCT00849628 Use of Drugs and Constipation in Nursing Homes https://ClinicalTrials.gov/show/NCT00849628 Completed Norwegian University of Science and Technology 2009-12-31
NCT00846794 AcuGraph and Digestive Symptoms https://ClinicalTrials.gov/show/NCT00846794 Completed Logan College of Chiropractic 2010-03-31
NCT01710904 A Non-interventional, Observational Study for Targinact® Treatment in Patients With Chronic Severe Pain https://ClinicalTrials.gov/show/NCT01710904 Completed Mundipharma CVA 2013-07-31
NCT03342287 Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation https://ClinicalTrials.gov/show/NCT03342287 Active, not recruiting McMaster University 2020-12-31
NCT02836717 Long Term Efficacy of Sacral Nerve Modulation (SNM) in Patients With Constipation or Stool Incontinence https://ClinicalTrials.gov/show/NCT02836717 Completed Cantonal Hospital of St. Gallen 2016-09-30
NCT01645371 Assessing a Stool Symptom Screener in Patients With Chronic Opioid-Induced Constipation https://ClinicalTrials.gov/show/NCT01645371 Completed AstraZeneca 2013-02-28
NCT04173858 Evaluation of the Quality of Life of Patients With Opioid-induced Constipation Under Treatment With Naloxegol https://ClinicalTrials.gov/show/NCT04173858 Completed Kyowa Kirin Farmacéutica S.L.U. 2019-10-31
NCT00728975 The Bowel Research Collaborative Data Tracking System Implementation Study https://ClinicalTrials.gov/show/NCT00728975 Completed British Columbia Cancer Agency 2010-02-28
NCT00677508 Development of an Instrument to Measure Quality of Life in Children With Chronic Constipation and Soiling https://ClinicalTrials.gov/show/NCT00677508 Completed Medical College of Wisconsin 2011-08-31
NCT00619125 Proposal Evaluating Time-specific Relationships Between Variables of Pain, Stress, and Bloating in IBS Diarrhea and Constipation Symptoms Using a Palm Pilot https://ClinicalTrials.gov/show/NCT00619125 Completed University of North Carolina, Chapel Hill 2009-03-31
NCT00603707 Assessment of Whole Gut Transit Time Using the SmartPill Capsule https://ClinicalTrials.gov/show/NCT00603707 Completed The SmartPill Corporation 2008-06-30
NCT00398021 Predictors of Constipation in Healthy Children https://ClinicalTrials.gov/show/NCT00398021 Completed University of Wisconsin, Madison 2009-06-30
NCT00230360 Diagnosis of Functional Defecation Disorders in Childhood https://ClinicalTrials.gov/show/NCT00230360 Completed University of Aarhus NA
NCT00032682 Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics https://ClinicalTrials.gov/show/NCT00032682 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02749682 Relationship Between Constipation and Inguinal Hernia https://ClinicalTrials.gov/show/NCT02749682 Completed Siverek Devlet Hastanesi 2015-07-31
NCT04415710 Pelvic Floor and Sexual Dysfunction in Women With Sjogren’s Syndrome https://ClinicalTrials.gov/show/NCT04415710 Completed Akdeniz University 2020-05-30
NCT04304183 Defecation Function and Quality of Life in the Patients Treated With Surgery for Slow Transit Constipation https://ClinicalTrials.gov/show/NCT04304183 Recruiting Third Military Medical University 2024-12-31